Response to comment on "the geometric structure of the brain fiber pathways".
نویسندگان
چکیده
In response to Catani et al., we show that corticospinal pathways adhere via sharp turns to two local grid orientations; that our studies have three times the diffusion resolution of those compared; and that the noted technical concerns, including crossing angles, do not challenge the evidence of mathematically specific geometric structure. Thus, the geometric thesis gives the best account of the available evidence.
منابع مشابه
Comment on "The geometric structure of the brain fiber pathways".
Wedeen et al. (Reports, 30 March 2012, p. 1628) proposed a geometrical grid pattern in the brain that could help the understanding of the brain's organization and connectivity. We show that whole-brain fiber crossing quantification does not support their theory. Our results suggest that the grid pattern is most likely an artifact attributable to the limitations of their method.
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ورودعنوان ژورنال:
- Science
دوره 337 6102 شماره
صفحات -
تاریخ انتشار 2012